Lysine in food supplements
771 supplements declared in France contain Lysine as a substance or active ingredient.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
BIOLOGICAL ACTIVITIES: Antialkalotic; antiherpetic; essential; hypoarginanemic
Biochemical and nutritional research, pharmaceuticals, culture media, fortification of foods and feed (wheat flour), nutrient and dietary supplement, animal feed additive
Enrichment of cereals and feeds.
Medical use: treatment of hypochloremia, alkalosis /lysine hydrochloride/
Reported uses
Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#3864]
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · USDA; Dr. Duke's Phytochemical and Ethnobotanical Databases. Plants with a chosen chemical. Lysine. Washington, DC: US Dept Agric, Agric Res Service. Available from, as of August 17, 2010: https://www.ars-grin.gov/duke/; Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 86 (1985); Burdock, G.A. (ed.). Fenaroli's Handbook of Flavor Ingredients. 6th ed.Boca Raton, FL 2010, p. 1110.
Use classification
Cosmetics -> Skin conditioning; Hair conditioning; Antistatic
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 119 taxa; examples: Morchella angusticeps, Morchella crassipes, Citrus grandis, Citrus medica, Pinus densiflora.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
A process combining chemical and microbiological techniques for the production of L-lysine was introduced by Toray Industries; /in this process/, alpha-amino-e-caprolactam (ACL) is formed from cyclohexanol... this intermediate is then hydrolyzed with L-ACL-hydrolase to yield L-lysine
Extraction of natural proteins, synthetically by fermentation of glucose or other carbohydrates and by synthesis from caprolactum
Isolation from acid-hydrolyzed proteins (casein, fibrin or blood corpuscle paste)
The usual raw material for the fermentation production of L-lysine is molasses...high performance microbes belong to the species Corynebacterium glutamicum or Brevibactrium lactofermentum
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 71 (1985); Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 887.
Appearance
Colorless crystals
Needles from water, hexagonal plates from dilute alcohol
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977.
Taste described
Sweet/bitter
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT05210504 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 3
COMPLETED · PHASE1 · Diabetes Mellitus, Type 2 · 2024-06-05 · L-Lysine
- NCT06580145 : Leucine in Midlife Depression
RECRUITING · PHASE2 · Major Depression · 2026-09-11 · L-lysine; L-lysine (synonym declared in the registry)
- NCT04417218 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 2
COMPLETED · NA · Healthy · 2023-12-21 · Lysine
2026-11-01
Other names: L-lysine (French), L-lysine (English).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: LYSINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Lysine) : sport (252 produits), cheveux et ongles (110 produits), peau (54 produits), articulations (42 produits), immunité (42 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 8 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 953 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 1330 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 133 | 480 | 0.009 | 7,400 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- INTRA ALTHEA NUTRITION, poudre, flavour citron, declared in 2025
- IRON PRE-WORKOUT ERIC FAVRE SPORT NUTRITION EXPERT, gélule, declared in 2016
- IRON PRE-WORKOUT ERIC FAVRE SPORT NUTRITION EXPERT, gélule, declared in 2016
- IRON PRE-WORKOUT ERIC FAVRE SPORT NUTRITION EXPERT, gélule, declared in 2016
- IRON ULTRA FAT BURNER gélule, declared in 2026
- Ico Amino Energy Framboise-Myrtille First Iron Systems, poudre, flavour framboise-myrtille, declared in 2019
- Ico Amino Energy Fruit de la Passion - Mangue First Iron Systems, poudre, flavour fruit de la passion - mangue, declared in 2020
- Ico Amino Energy Mangue-Ananas First Iron Systems, poudre, flavour mangue-ananas, declared in 2019
- Icobolic Tropical First Iron Systems, poudre, flavour tropical, declared in 2016
- Idéale autre : comprimés effervescents, declared in 2025
- Immune 360 Biocyte, gélule, declared in 2026
- Imunix + Bêta-Glucanes GreenFood Nutrition, gélule, declared in 2025
- Intra EAA Fit & Healthy, poudre, flavour pastèque, declared in 2022
- Intra EAA Fit & Healthy, poudre, flavour fruits rouges, declared in 2022
- Intra Workout, Peach Iced Tea poudre, declared in 2026
- Iron performance gélule, declared in 2025
- IxeaBoost Multi Premium Nutrixeal, gélule, declared in 2022
- KERATINE PLUS VIE & NUTRITION, gélule, declared in 2016
- KERATINE PRO PLUS gélule, declared in 2025
- KETOAMIN BIOROSAN, comprimé, declared in 2025
- KITOSOME MAXINERGIE gélule, declared in 2023
- Kailuxe BioEssentials, gélule, declared in 2026
- L- lysine Bioherba, gélule, declared in 2025
- L-Biome gélule, declared in 2023
- L-CARNITINE '(5) ABSOLUT_S, flacon, flavour citrique, declared in 2024
- L-ERGOTHIONÉINE RealmNutrition, gélule, declared in 2025
- L-LYSINE Dieti Natura, comprimé, declared in 2023
- L-LYSINE gélule, declared in 2022
- L-LYSINE NOW FOODS, poudre, flavour nature, declared in 2016
- L-LYSINE dieti natura, comprimé, declared in 2025
- L-LYSINE 500 SFB, gélule, declared in 2020
- L-LYSINE ÉQUILIBRE PREMIUM gélule, declared in 2024
- L-Lysine gélule, declared in 2023
- L-Lysine poudre, declared in 2022
- L-Lysine poudre, flavour sans saveur, declared in 2021
- L-Lysine Zerex, gélule, declared in 2026
- L-Lysine gélule, declared in 2026
- L-Lysine Nutrilife, gélule, declared in 2025
- L-Lysine 1000mg Now Foods, comprimé, declared in 2021
- L-Lysine 100g poudre, declared in 2020
- L-Lysine en poudre 120g NutriZoé, poudre, flavour naturel, declared in 2021
- L-lysine Nutrixeal, comprimé, flavour néant, declared in 2016
- L-lysine LUTO Supplements, pilule, declared in 2025
- L-lysine Biotikon, capsule, flavour neutre, declared in 2023
- L-lysine gélule, declared in 2016
- L-lysine 1000 Kersiens, gélule, declared in 2024
- L-lysine 1000 µg gélule, declared in 2024
- L-lysine et l-proline Hanoju, gélule, declared in 2017
- LE COMPLÉMENT Pousse et Fortification Ludivine Hair, gélule, declared in 2026
- LIPOPHEDRINE gélule, declared in 2023
- LIPOXYNE ERIC FAVRE LABORATOIRE, gélule, declared in 2021
- LONG & BEAUTY gélule, declared in 2017
- LYSINE LABOFLORAL, gélule, declared in 2020
- LYSINE poudre, declared in 2019
- LYSINE 1000 mg Solgar, comprimé, declared in 2025
- LYSINE 800 comprimé, declared in 2016
- La Formule Précise - The Precise Formula Hair Full Cycle, gélule, declared in 2022
- LipidActif Nutrixeal, gélule, declared in 2022
- Lipoate R complex gélule, declared in 2026
- Liposomal Multi Amino Codeage, gélule, declared in 2026