Lysine in food supplements
771 supplements declared in France contain Lysine as a substance or active ingredient.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
BIOLOGICAL ACTIVITIES: Antialkalotic; antiherpetic; essential; hypoarginanemic
Biochemical and nutritional research, pharmaceuticals, culture media, fortification of foods and feed (wheat flour), nutrient and dietary supplement, animal feed additive
Enrichment of cereals and feeds.
Medical use: treatment of hypochloremia, alkalosis /lysine hydrochloride/
Reported uses
Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#3864]
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · USDA; Dr. Duke's Phytochemical and Ethnobotanical Databases. Plants with a chosen chemical. Lysine. Washington, DC: US Dept Agric, Agric Res Service. Available from, as of August 17, 2010: https://www.ars-grin.gov/duke/; Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 86 (1985); Burdock, G.A. (ed.). Fenaroli's Handbook of Flavor Ingredients. 6th ed.Boca Raton, FL 2010, p. 1110.
Use classification
Cosmetics -> Skin conditioning; Hair conditioning; Antistatic
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 119 taxa; examples: Morchella angusticeps, Morchella crassipes, Citrus grandis, Citrus medica, Pinus densiflora.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
A process combining chemical and microbiological techniques for the production of L-lysine was introduced by Toray Industries; /in this process/, alpha-amino-e-caprolactam (ACL) is formed from cyclohexanol... this intermediate is then hydrolyzed with L-ACL-hydrolase to yield L-lysine
Extraction of natural proteins, synthetically by fermentation of glucose or other carbohydrates and by synthesis from caprolactum
Isolation from acid-hydrolyzed proteins (casein, fibrin or blood corpuscle paste)
The usual raw material for the fermentation production of L-lysine is molasses...high performance microbes belong to the species Corynebacterium glutamicum or Brevibactrium lactofermentum
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 71 (1985); Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 887.
Appearance
Colorless crystals
Needles from water, hexagonal plates from dilute alcohol
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977.
Taste described
Sweet/bitter
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT05210504 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 3
COMPLETED · PHASE1 · Diabetes Mellitus, Type 2 · 2024-06-05 · L-Lysine
- NCT06580145 : Leucine in Midlife Depression
RECRUITING · PHASE2 · Major Depression · 2026-09-11 · L-lysine; L-lysine (synonym declared in the registry)
- NCT04417218 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 2
COMPLETED · NA · Healthy · 2023-12-21 · Lysine
2026-11-01
Other names: L-lysine (French), L-lysine (English).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: LYSINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Lysine) : sport (252 produits), cheveux et ongles (110 produits), peau (54 produits), articulations (42 produits), immunité (42 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 8 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 953 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 1330 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 133 | 480 | 0.009 | 7,400 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- Mineral Vit Magnum Be-Life, gélule, declared in 2017
- Mirage Sport ELEMENTAL Amino Energy pink grapefruit GALVANIZE NUTRITION, poudre, flavour pink grapefruit, declared in 2018
- Mirage Sport Elemental Amino Energy Tropical punch GALVANIZE NUTRITION, poudre, flavour tropical punch, declared in 2018
- Multi Amino-EAA (BLUEBERRY CRYSTAL) poudre, flavour blueberry crystal, declared in 2021
- Multi Amino-EAA (Cola-Lemon) poudre, flavour cola-lemon, declared in 2021
- Multi Amino-EAA (LEMON CANDY) poudre, flavour lemon candy, declared in 2021
- Multi Amino-EAA (Strawberry and Watermelon) poudre, flavour strawberry and watermelon, declared in 2021
- Multiregen EX origen pure, poudre, declared in 2018
- Multivitamin Fruit&Veggie gélule, declared in 2023
- Multivitamines VITAVEA, comprimé, declared in 2023
- Multivitaminée comprimé, declared in 2026
- MyAmino Dr. Reinwald vital, comprimé, declared in 2025
- NERVIAL capsule, declared in 2019
- NERVIALIS OXIBIOTIK NUTRITION®, capsule, declared in 2022
- NERVIALIS® capsule, declared in 2021
- NUTRA'SOLAIRE MINOLVIE, gélule, declared in 2026
- NUTRI CAPILLAIRE gélule, declared in 2023
- NUTRI PNEA NUTRILAB, comprimé, declared in 2022
- NUTRICAP KÉRATINE VITAVEA - Laboratoires Nutrisanté, gélule, declared in 2024
- Natur'Phan+ comprimé, declared in 2019
- Novomins Vegan Collagen Gummies Novomins, gomme à mâcher, flavour fruit de la passion acidulé, declared in 2026
- Nutri Endo Plus Laboratoires Activa, gélule, declared in 2026
- Nutri Endo Plus Laboratoires Nutrilab, gélule, declared in 2025
- Nutri Pnea Plus Laboratoires Nutrilab, gélule, declared in 2025
- Nutri+Cheveux et ongles Exhalessence, gélule, declared in 2025
- Nutri-Hydrate poudre, declared in 2025
- Nutri-Plus EAA Essential Aminos Framboise Bonbon glacé Nutri-Plus, poudre, flavour framboise bonbon glacé, declared in 2023
- Nutri-Plus EAA Essential Aminos Sour Peaches Nutri-Plus, poudre, flavour pêches acides, declared in 2023
- NutriProtect Detox poudre, declared in 2024
- Nutribiote Base flacon, declared in 2025
- Nutribiote Base flacon, declared in 2023
- Nutricap croissance Vitavea Laboratoires Nutrisanté, gélule, declared in 2024
- Nutrition Capillaire D-LAB NUTRICOSMETICS, autre : absolu de kératine: comprimés & complexe de pousse : gélules, declared in 2023
- Nutrition-Capillaire D-LAB Nutricosmetics, gélule, declared in 2019
- N°14 CAPITAL ONGLES & CHEVEUX EQUI-NUTRI, gélule, declared in 2018
- N°15 MENO 50+ EQUI-NUTRI, gélule, declared in 2018
- OCARE ARTICULATIONS poudre, declared in 2023
- OLIGOBASE EQUILIBRE, gélule, declared in 2025
- OLIGOBASE EQUILIBRE, gélule, declared in 2022
- OLIGOVie CSBS ODEMER, gélule, declared in 2025
- OROPEP's EPITIDE granule, declared in 2016
- OROPEP's EPITIDE granule, flavour citron et fraise, declared in 2016
- OROPEP's EPITIDE granule, declared in 2016
- OSTEO CODE® autre : comprimé effervescent, declared in 2024
- Ongles et Cheveux gélule, declared in 2016
- Ongles et Cheveux gélule, declared in 2016
- Oscillo'immunité BOIRON, comprimé, declared in 2024
- OstéoRenov Lorica, bâton / batônnet / stick, declared in 2025
- OstéoRénov Pot LORICA, poudre, flavour fruits exotiques, declared in 2026
- PARUSEN gélule, declared in 2023
- PARUSEN 90 gélule, declared in 2024
- PEAU bâton / batônnet / stick, declared in 2024
- PEAU, ONGLES CHEVEUX Solgar, comprimé, declared in 2025
- PEAU, ONGLES, CHEVEUX ABINTUS, gélule, declared in 2020
- PHYTONUTRI PH gélule, declared in 2025
- POST- PARTUM gélule, declared in 2026
- POUSSE CHEVEUX Natural MB'Fit, gélule, declared in 2023
- POUSSE CHEVEUX ALICE PARIS, gélule, declared in 2026
- POUSSE CHEVEUX gélule, declared in 2025
- POUSSE Cheveux LM NUTRI, gélule, declared in 2025