Lysine in food supplements
771 supplements declared in France contain Lysine as a substance or active ingredient.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
BIOLOGICAL ACTIVITIES: Antialkalotic; antiherpetic; essential; hypoarginanemic
Biochemical and nutritional research, pharmaceuticals, culture media, fortification of foods and feed (wheat flour), nutrient and dietary supplement, animal feed additive
Enrichment of cereals and feeds.
Medical use: treatment of hypochloremia, alkalosis /lysine hydrochloride/
Reported uses
Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#3864]
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · USDA; Dr. Duke's Phytochemical and Ethnobotanical Databases. Plants with a chosen chemical. Lysine. Washington, DC: US Dept Agric, Agric Res Service. Available from, as of August 17, 2010: https://www.ars-grin.gov/duke/; Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 86 (1985); Burdock, G.A. (ed.). Fenaroli's Handbook of Flavor Ingredients. 6th ed.Boca Raton, FL 2010, p. 1110.
Use classification
Cosmetics -> Skin conditioning; Hair conditioning; Antistatic
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 119 taxa; examples: Morchella angusticeps, Morchella crassipes, Citrus grandis, Citrus medica, Pinus densiflora.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
A process combining chemical and microbiological techniques for the production of L-lysine was introduced by Toray Industries; /in this process/, alpha-amino-e-caprolactam (ACL) is formed from cyclohexanol... this intermediate is then hydrolyzed with L-ACL-hydrolase to yield L-lysine
Extraction of natural proteins, synthetically by fermentation of glucose or other carbohydrates and by synthesis from caprolactum
Isolation from acid-hydrolyzed proteins (casein, fibrin or blood corpuscle paste)
The usual raw material for the fermentation production of L-lysine is molasses...high performance microbes belong to the species Corynebacterium glutamicum or Brevibactrium lactofermentum
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 71 (1985); Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 887.
Appearance
Colorless crystals
Needles from water, hexagonal plates from dilute alcohol
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977.
Taste described
Sweet/bitter
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT05210504 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 3
COMPLETED · PHASE1 · Diabetes Mellitus, Type 2 · 2024-06-05 · L-Lysine
- NCT06580145 : Leucine in Midlife Depression
RECRUITING · PHASE2 · Major Depression · 2026-09-11 · L-lysine; L-lysine (synonym declared in the registry)
- NCT04417218 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 2
COMPLETED · NA · Healthy · 2023-12-21 · Lysine
2026-11-01
Other names: L-lysine (French), L-lysine (English).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: LYSINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Lysine) : sport (252 produits), cheveux et ongles (110 produits), peau (54 produits), articulations (42 produits), immunité (42 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 8 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 953 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 1330 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 133 | 480 | 0.009 | 7,400 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- EAA AMINO FRENCH LA FRENCH Nutrition, poudre, flavour pomme, declared in 2022
- EAA AMINO FRENCH LA FRENCH Nutrition, poudre, flavour cerise, declared in 2022
- EAA ENDURANCE poudre, declared in 2019
- EAA Electrolytes Zero BioTechUSA Kft., poudre, flavour bonbon cerise, declared in 2026
- EAA Electrolytes Zero BioTechUSA Kft., poudre, flavour orange, declared in 2026
- EAA MAXX BODYMAXX SPORTS NUTRITION, poudre, flavour pomme verte, declared in 2020
- EAA MAXX BODYMAXX SPORTS NUTRITION, poudre, flavour citrus, declared in 2020
- EAA MEGA STRONG POWDER NUTREND, poudre, flavour ananas + poire, declared in 2019
- EAA MEGA STRONG POWDER NUTREND, poudre, flavour orange + pomme, declared in 2019
- EAA Perfect Insport Nutrition, poudre, declared in 2024
- EAA Perfect Insport Nutrition, poudre, flavour pamplemousse, declared in 2024
- EAA Perfect Insport Nutrition, poudre, flavour cola, declared in 2024
- EAA Perfect Insport Nutrition, poudre, flavour energy drink, declared in 2024
- EAA Plus (Comprimé) Myprotein, comprimé, flavour sans arôme, declared in 2016
- EAA Powder Empose Nutrition, poudre, flavour peach tea, declared in 2022
- EAA Powder Empose Nutrition, poudre, flavour cherry, declared in 2022
- EAA XPRESS Scitec Nutrition, poudre, flavour non-aromatisée, declared in 2022
- EAA XPRESS Scitec Nutrition, poudre, flavour thé glacé à la pêche, declared in 2021
- EAA XPRESS Scitec Nutrition, poudre, flavour pink limonade, declared in 2021
- EAA XPRESS Scitec Nutrition, poudre, flavour fruits tropicaux, declared in 2021
- EAA XPRESS Scitec Nutrition, poudre, flavour pasteque-fraise, declared in 2021
- EAA XPRESS Scitec Nutrition, poudre, flavour kiwi-lime, declared in 2021
- EAA XPRESS Scitec Nutrition, poudre, flavour thé glacé à la pêche, declared in 2021
- EAA Xpress Scitec Nutrition, poudre, flavour pomme verte – yuzu, declared in 2026
- EAA Zero BiotechUSA, poudre, flavour non-aromatisée, declared in 2022
- EAA – Mangue-Maracuja – GymBeam - 250g GymBeam, poudre, flavour mangue-maracuja, declared in 2026
- EAA'S COMPLEX comprimé, declared in 2018
- EAA'S COMPLEX poudre, flavour fruit de la foret, declared in 2018
- EAA+Glutamine Xpress Scitec Nutrition, poudre, flavour melon coke, declared in 2025
- EAA+Glutamine Xpress Scitec Nutrition, poudre, flavour mangue, declared in 2025
- EAA+Glutamine Xpress Scitec Nutrition, poudre, flavour cherry-lime, declared in 2025
- EAA+Glutamine Xpress Scitec Nutrition, poudre, flavour pink limonade, declared in 2025
- EAA-Powder MAXI NUTRITION, poudre, flavour tropical, declared in 2024
- EAA7pro CF7 sport nutrition, poudre, flavour candy cola, declared in 2021
- EAA7pro CF7 sport nutrition, poudre, flavour lollypop, declared in 2021
- EAA7pro CF7 sport nutrition, poudre, flavour fruits rouges, declared in 2021
- EAA7pro CF7 sport nutrition, poudre, flavour pêche, declared in 2021
- EAACORE GENIUS, poudre, flavour pomme, declared in 2018
- EAAMMO poudre, declared in 2019
- EAAS LIFE PRO, poudre, flavour tropical, declared in 2022
- EAAS LIFE PRO, poudre, flavour groseille, declared in 2022
- EAAS LIFE PRO, poudre, flavour citron, declared in 2022
- EAAs Wheyland, autre : capsules, declared in 2025
- EAAs (ACID LEMON FLAVOUR) poudre, declared in 2025
- EAAs (FRUIT BLAST) LIFE PRO, poudre, flavour fruit blast, declared in 2025
- EAAs (TROPICAL) LIFE PRO, poudre, flavour tropical, declared in 2025
- EAAs + Electrolytes Dymatize, poudre, flavour blue raspberry flavour, declared in 2026
- EAAs + Electrolytes Dymatize, poudre, flavour apple lime flavour, declared in 2026
- EFFLUVIUM CONTROL Make My Mask, gélule, declared in 2026
- ENERGY EAA GEN GERMAN ELITE NUTRITION, poudre, flavour citron, declared in 2024
- ENERGY EAA GEN GERMAN ELITE NUTRITION, poudre, flavour thé glacé à la pêche, declared in 2024
- ENERGY EAA GEN GERMAN ELITE NUTRITION, poudre, flavour gallium, declared in 2024
- ENERGY EAA GEN GERMAN ELITE NUTRITION, poudre, flavour pomme verte, declared in 2024
- ERGYCAPIL gélule, declared in 2022
- ERGYCARTIL FORT Nutergia, sachet, declared in 2017
- ERIC FAVRE LABORATOIRE SPECIAL GROWTH LIQUIDE CALCIUM autre : stick, flavour pêche, declared in 2026
- ERIC FAVRE LABORATOIRE SPECIALKID Stick Calcium Magnésium Zinc + Acides aminés autre : stick, declared in 2026
- ESN EAA+ Blackberry Flavor poudre, flavour blackberry flavor, declared in 2026
- ESN EAA+ Green Apple Flavor poudre, declared in 2026
- ESN EAA+ Lemon Iced Tea Flavor poudre, flavour lemon iced tea flavor, declared in 2026
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