Nicotinamide (vitamin B3) in food supplements
8,647 supplements declared in France contain a form of this nutrient
Nicotinamide: in France, a food supplement may not provide more than 54 mg a day (Order of 9 May 2006, not revised since November 2006, Annex III); for adults, EFSA's upper safe limit is 900 mg a day. The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Written Question No 2686, ministry answer published in the Official Journal on 11 February 2025.
What we know about this ingredient
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT04844528 : Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers
RECRUITING · PHASE2 · Chronic Lymphocytic Leukemia, Non-melanoma Skin Cancer (NMSC) · 2025-12-03 · Nicotinamide
- NCT07585006 : Comparative Evaluation of Nicotine Analogs
RECRUITING · PHASE1 · Tobacco-Related Carcinoma, Addiction · 2026-06-26 · nicotinamide
- NCT07808333 : Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial)
NOT_YET_RECRUITING · PHASE2 · Glaucoma, Open-angle, Primary Open Angle Glaucoma (POAG) · 2026-10-13 · Nicotinamide
2026-11-01
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (nicotinamide (vitamine B3)) : sport (1112 produits), immunité (1052 produits), système nerveux (761 produits), cheveux et ongles (735 produits), peau (695 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
Jusqu'où c'est sûr
Pour un adulte, l'EFSAEuropean Food Safety Authority. fixe la limite supérieure de sécurité à 900 mg/j : c'est l'apport quotidien qui, pris sur le long terme, toutes sources alimentaires réunies, ne devrait pas provoquer d'effet indésirable. Au-delà, le risque augmente. Un complément n'est qu'une partie de l'apport.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
La règle en France
En France, la dose journalière recommandée d'un complément ne doit pas apporter plus de 54 mg (arrêté du 9 mai 2006, non révisé depuis novembre 2006). Compl'Alim ne publie pas la dose des produits déclarés : comparez celle de l'étiquette à ce plafond et à la limite de sécurité de l'EFSA.
French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA safety references
Le repère de l'EFSA porte sur l'apport total d'une journée, alimentation et compléments.
| Population | Type | Value |
|---|---|---|
| 1-3 years | Upper limit | 150 mg/j |
| 4-6 years | Upper limit | 220 mg/j |
| 7-10 years | Upper limit | 350 mg/j |
| 11-14 years | Upper limit | 500 mg/j |
| 15-17 years | Upper limit | 700 mg/j |
| adults | Upper limit | 900 mg/j |
| pregnancy | Upper limit | inadequate data |
| breastfeeding | Upper limit | inadequate data |
SCF, 2002a. EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Maximum dose in France
Maximum daily dose per supplement in France: 54 mg, according to the Order of 9 May 2006.
The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
Forms declared in supplements
Union list: vitamin and mineral forms that may be used in a food supplement (Directive 2002/46/EC, Annex II).
Directive 2002/46/EC on food supplements, latest consolidated version (Annex II: forms of vitamins and minerals), retrieved 23 October 2026.
- Nicotinamide 8,534 products on the Union list
- Chlorure de nicotinamide riboside 135 products on the Union list
In cosmetics: NIACINAMIDE.
Products containing it
- FORTIFIANT comprimé, withdrawn from the market
- FORTIFIANT CAPILLAIRE comprimé, withdrawn from the market
- Femibion Grossesse Metafolin comprimé, withdrawn from the market
- Femibion Grossesse Metafolin+DHA autre : comprimé + capsule, withdrawn from the market
- Femilyane Neolya Grossesse et Allaitement - comprimé Femilyane, comprimé, withdrawn from the market
- Feminabiane conception Pileje, autre : comprimés et capsules, withdrawn from the market
- Fer + Vitamines B Pharm & Nature, sirop, withdrawn from the market
- Fertivital gélule, withdrawn from the market
- FitLine Activize Sensitive FitLine, poudre, flavour cassis, withdrawn from the market
- Fluidil NUTRISVELT, gélule, withdrawn from the market
- Focus STIMIUM, gomme, flavour citron, withdrawn from the market
- Force G Naturelle Laboratoires Nutrisanté, comprimé, withdrawn from the market
- Formula 2 - Complexe vitamines & minéraux femme comprimé, withdrawn from the market
- Formula 2 - Complexe vitamines & minéraux homme comprimé, withdrawn from the market
- Forti+ Dieti Natura, gélule, withdrawn from the market
- Forté Stress 24 h Forté Pharma, comprimé, withdrawn from the market
- GLOW FLOW ActiThea, poudre, flavour hibiscus - fruits rouges - fleur de sureau, withdrawn from the market
- GLUCOMANNAN NUTRALIE, capsule, withdrawn from the market
- GLUCOMANNAN NUTRIDIX, capsule, withdrawn from the market
- GLUCOMANNAN COMPLEX Nutralie, capsule, withdrawn from the market
- GLUCOMANNAN COMPLEX Nutralie, gélule, withdrawn from the market
- GLUTAPROTECT Laboratoires Synactifs, poudre, withdrawn from the market
- GREEN ANGEL VITAnutrition, bâton / batônnet / stick, withdrawn from the market
- GREEN ANGEL sachet, withdrawn from the market
- GROSSESSE gélule, withdrawn from the market
- Gakbe & Courbe gélule, withdrawn from the market
- Gametix F Densmore laboratoires, sachet, withdrawn from the market
- Gametix F sachet, withdrawn from the market
- Gametix F sachet, withdrawn from the market
- Gametix M Densmore laboratoires, sachet, withdrawn from the market
- Gametix M sachet, withdrawn from the market
- Genius.Actifs SYNActifs, comprimé, withdrawn from the market
- Germag Lorica, comprimé, withdrawn from the market
- Germag Lorica, sachet, flavour abricot, withdrawn from the market
- Germag Lorica, gélule, withdrawn from the market
- Gestagyn® Grossesse capsule, withdrawn from the market
- Gestagyn® Plus New capsule, withdrawn from the market
- Giseng Gelée Royale ampoule, withdrawn from the market
- Gluco-Nut D.Plantes, gélule, withdrawn from the market
- Guard BRAINEFFECT, capsule, withdrawn from the market
- Gummies Multi'Vit Adulte gomme, withdrawn from the market
- Gummies VITALITE Valda, gomme, flavour arôme naturel - goût fruits des bois, withdrawn from the market
- Gummies VITALITE Valda, gomme, flavour arôme naturel - goût myrtille, withdrawn from the market
- Gynefam Supra capsule, withdrawn from the market
- Gynefam Supra Gynefam, capsule, withdrawn from the market
- Gynefam supra grossesse oro gynefam, sachet, flavour citron, withdrawn from the market
- Gélule de L-EGT FÉLICIA BEAUTÉ, gélule, flavour non spécifiée, withdrawn from the market
- Gélules Vitalité gélule, withdrawn from the market
- HAARFÜLLE nu3, gélule, withdrawn from the market
- HAIR + NAILS COMPLETE Ultimate Skin Aesthetics, gélule, withdrawn from the market
- HAIR BOOSTER PLUS ELLIKRIL, gélule, withdrawn from the market
- HEPATINOV EFFINOV, flacon, withdrawn from the market
- HOMME FERTILE gélule, withdrawn from the market
- HORBÄACH - HAPPY GUT ADULT GUMMIES HORBÄACH, gomme à mâcher, withdrawn from the market
- HORMO BALANCE gélule, withdrawn from the market
- HSN CARE (HAIR, SKIN AND NAILS COMPLEX) HSN, capsule, withdrawn from the market
- HYPERVITE HERO TECH NUTRITION, gélule, withdrawn from the market
- Healthy Hair Vitamins Hairburst, gélule, withdrawn from the market
- Herbesan Gelée royale et 12 vitamines + 1 minéral avec édulcorant Herbesan, comprimé, withdrawn from the market
- HoliBoost gélule, withdrawn from the market