Nicotinamide (vitamin B3) in food supplements
8,647 supplements declared in France contain a form of this nutrient
Nicotinamide: in France, a food supplement may not provide more than 54 mg a day (Order of 9 May 2006, not revised since November 2006, Annex III); for adults, EFSA's upper safe limit is 900 mg a day. The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Written Question No 2686, ministry answer published in the Official Journal on 11 February 2025.
What we know about this ingredient
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT04844528 : Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers
RECRUITING · PHASE2 · Chronic Lymphocytic Leukemia, Non-melanoma Skin Cancer (NMSC) · 2025-12-03 · Nicotinamide
- NCT07585006 : Comparative Evaluation of Nicotine Analogs
RECRUITING · PHASE1 · Tobacco-Related Carcinoma, Addiction · 2026-06-26 · nicotinamide
- NCT07808333 : Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial)
NOT_YET_RECRUITING · PHASE2 · Glaucoma, Open-angle, Primary Open Angle Glaucoma (POAG) · 2026-10-13 · Nicotinamide
2026-11-01
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (nicotinamide (vitamine B3)) : sport (1112 produits), immunité (1052 produits), système nerveux (761 produits), cheveux et ongles (735 produits), peau (695 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
Jusqu'où c'est sûr
Pour un adulte, l'EFSAEuropean Food Safety Authority. fixe la limite supérieure de sécurité à 900 mg/j : c'est l'apport quotidien qui, pris sur le long terme, toutes sources alimentaires réunies, ne devrait pas provoquer d'effet indésirable. Au-delà, le risque augmente. Un complément n'est qu'une partie de l'apport.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
La règle en France
En France, la dose journalière recommandée d'un complément ne doit pas apporter plus de 54 mg (arrêté du 9 mai 2006, non révisé depuis novembre 2006). Compl'Alim ne publie pas la dose des produits déclarés : comparez celle de l'étiquette à ce plafond et à la limite de sécurité de l'EFSA.
French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA safety references
Le repère de l'EFSA porte sur l'apport total d'une journée, alimentation et compléments.
| Population | Type | Value |
|---|---|---|
| 1-3 years | Upper limit | 150 mg/j |
| 4-6 years | Upper limit | 220 mg/j |
| 7-10 years | Upper limit | 350 mg/j |
| 11-14 years | Upper limit | 500 mg/j |
| 15-17 years | Upper limit | 700 mg/j |
| adults | Upper limit | 900 mg/j |
| pregnancy | Upper limit | inadequate data |
| breastfeeding | Upper limit | inadequate data |
SCF, 2002a. EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Maximum dose in France
Maximum daily dose per supplement in France: 54 mg, according to the Order of 9 May 2006.
The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
Forms declared in supplements
Union list: vitamin and mineral forms that may be used in a food supplement (Directive 2002/46/EC, Annex II).
Directive 2002/46/EC on food supplements, latest consolidated version (Annex II: forms of vitamins and minerals), retrieved 23 October 2026.
- Nicotinamide 8,534 products on the Union list
- Chlorure de nicotinamide riboside 135 products on the Union list
In cosmetics: NIACINAMIDE.
Products containing it
- Hot Blood 3.0 poudre, flavour guarana bleu, withdrawn from the market
- Hot Blood 3.0 poudre, flavour orange maracuja, withdrawn from the market
- Hot Blood 3.0 poudre, flavour limonade rose, withdrawn from the market
- Hot Blood 3.0 poudre, flavour orange sanguine, withdrawn from the market
- Hot Blood 3.0 poudre, flavour jus d'orange, withdrawn from the market
- Hot Blood Hardcore No-Stim poudre, flavour orange, withdrawn from the market
- Hot Blood Hardcore No-Stim poudre, flavour tropical punch, withdrawn from the market
- HydraBoost Fruits Rouges VITAVEA - Laboratoires Vitarmonyl, comprimé, withdrawn from the market
- HydraBoost Pêche Laboratoires Vitarmonyl, comprimé, withdrawn from the market
- Hépactiv comprimé, withdrawn from the market
- Hépato process - matin poudre, withdrawn from the market
- ID-Sun gélule, withdrawn from the market
- ILAFLORE LABORATOIRES ILAPHARM, gélule, withdrawn from the market
- ILAFLORE LABORATOIRES ILAPHARM, gélule, withdrawn from the market
- ILAFORM + LABORATOIRES ILAPHARM, poudre, withdrawn from the market
- ILOBOOST Laboratoires Ilapharm, gélule, withdrawn from the market
- ILOBOOST Laboratoires Ilapharm, gélule, withdrawn from the market
- IMMUNIREL autre : réparti en deux compartiments : bouchon avec un mélange de poudre et un flacon avec partie liquide, withdrawn from the market
- IMMUNIREL Laboratoire Santarel, autre : réparti en deux compartiments : bouchon avec un mélange de poudre et un flacon avec partie liquide, withdrawn from the market
- IMMUNOBOOST Complément alimentaire Immunité FREDERIC M, sachet, withdrawn from the market
- IMPRYL® comprimé, withdrawn from the market
- INTEGRAL B VIT'ALL +, comprimé, withdrawn from the market
- INTESTINOV EFFINOV NUTRITION, bâton / batônnet / stick, flavour agrumes, withdrawn from the market
- IQ Balance Day Physalis, comprimé, withdrawn from the market
- ISOMENOX comprimé, withdrawn from the market
- ISOXAN JUNIOR ISOXAN, granule, flavour fruits rouges, withdrawn from the market
- ISOXAN VITALITE JUNIOR ISOXAN VITALITE JUNIOR, granule, flavour fruits rouges, withdrawn from the market
- ISOXAN VITALITE SENIOR ISOXAN VITALITE SENIOR, comprimé, withdrawn from the market
- Immuno-muqueuse Dr Jacob's®, poudre, flavour oui, withdrawn from the market
- Inflamgut process matin poudre, withdrawn from the market
- Innovit Sun gummies gomme, flavour orange, withdrawn from the market
- Intelectio capsule, withdrawn from the market
- Isoxan 5 Nutri Adulte Isoxan, sachet, flavour orange, withdrawn from the market
- Isoxan 5 Nutri Junior Isoxan, sachet, flavour fruits rouges, withdrawn from the market
- JN comprimé, withdrawn from the market
- K-MATAB gélule, withdrawn from the market
- KERATINE FORTE 500 mg gélule, withdrawn from the market
- KERATINE FORTE ANTI-CHUTE gélule, withdrawn from the market
- KERATINE FORTE FULL SPECTRUM gélule, withdrawn from the market
- KETO3 capsule, withdrawn from the market
- KETOSLIM MAX ULTRA THERMOGENIC poudre, withdrawn from the market
- KID 23 VITAMINES, MINERAUX ET PLANTES GRANIONS, flacon, flavour tutti frutti, withdrawn from the market
- KID 23 VITAMINES, MINERAUX ET PLANTES GRANIONS, flacon, flavour tutti frutti, withdrawn from the market
- KOLESTEROL AROMA CELTE, gélule, withdrawn from the market
- Kera Concept Lorica, gélule, withdrawn from the market
- Kera'Boost Biform, gélule, withdrawn from the market
- Keratine Actidiet, gélule, withdrawn from the market
- Keratine Actidiet, gélule, withdrawn from the market
- Kijimea® FloraCare gélule, withdrawn from the market
- Kijimea® K53 Advance Kijimea®, gélule, withdrawn from the market
- Kinder Multivitamins flacon, flavour orange, withdrawn from the market
- Koleregul Complex Vitaminor, gélule, withdrawn from the market
- Kératine Laboratoires Yves Ponroy, gélule, withdrawn from the market
- Kératine + gélule, withdrawn from the market
- L TRYPTOPHANE 350 gélule, withdrawn from the market
- L-CARNITINE COMPLEX capsule, withdrawn from the market
- L-TRYPTOPHAN 500 MG HSN, capsule, withdrawn from the market
- L-TRYPTOPHAN 500MG VITAMINALIA, comprimé, withdrawn from the market
- LAMULTY LAVYTÉ, comprimé, withdrawn from the market
- LE MULTI gélule, withdrawn from the market