Nicotinamide (vitamin B3) in food supplements
8,647 supplements declared in France contain a form of this nutrient
Nicotinamide: in France, a food supplement may not provide more than 54 mg a day (Order of 9 May 2006, not revised since November 2006, Annex III); for adults, EFSA's upper safe limit is 900 mg a day. The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Written Question No 2686, ministry answer published in the Official Journal on 11 February 2025.
What we know about this ingredient
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT04844528 : Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers
RECRUITING · PHASE2 · Chronic Lymphocytic Leukemia, Non-melanoma Skin Cancer (NMSC) · 2025-12-03 · Nicotinamide
- NCT07585006 : Comparative Evaluation of Nicotine Analogs
RECRUITING · PHASE1 · Tobacco-Related Carcinoma, Addiction · 2026-06-26 · nicotinamide
- NCT07808333 : Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial)
NOT_YET_RECRUITING · PHASE2 · Glaucoma, Open-angle, Primary Open Angle Glaucoma (POAG) · 2026-10-13 · Nicotinamide
2026-11-01
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (nicotinamide (vitamine B3)) : sport (1112 produits), immunité (1052 produits), système nerveux (761 produits), cheveux et ongles (735 produits), peau (695 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
Jusqu'où c'est sûr
Pour un adulte, l'EFSAEuropean Food Safety Authority. fixe la limite supérieure de sécurité à 900 mg/j : c'est l'apport quotidien qui, pris sur le long terme, toutes sources alimentaires réunies, ne devrait pas provoquer d'effet indésirable. Au-delà, le risque augmente. Un complément n'est qu'une partie de l'apport.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
La règle en France
En France, la dose journalière recommandée d'un complément ne doit pas apporter plus de 54 mg (arrêté du 9 mai 2006, non révisé depuis novembre 2006). Compl'Alim ne publie pas la dose des produits déclarés : comparez celle de l'étiquette à ce plafond et à la limite de sécurité de l'EFSA.
French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA safety references
Le repère de l'EFSA porte sur l'apport total d'une journée, alimentation et compléments.
| Population | Type | Value |
|---|---|---|
| 1-3 years | Upper limit | 150 mg/j |
| 4-6 years | Upper limit | 220 mg/j |
| 7-10 years | Upper limit | 350 mg/j |
| 11-14 years | Upper limit | 500 mg/j |
| 15-17 years | Upper limit | 700 mg/j |
| adults | Upper limit | 900 mg/j |
| pregnancy | Upper limit | inadequate data |
| breastfeeding | Upper limit | inadequate data |
SCF, 2002a. EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Maximum dose in France
Maximum daily dose per supplement in France: 54 mg, according to the Order of 9 May 2006.
The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
Forms declared in supplements
Union list: vitamin and mineral forms that may be used in a food supplement (Directive 2002/46/EC, Annex II).
Directive 2002/46/EC on food supplements, latest consolidated version (Annex II: forms of vitamins and minerals), retrieved 23 October 2026.
- Nicotinamide 8,534 products on the Union list
- Chlorure de nicotinamide riboside 135 products on the Union list
In cosmetics: NIACINAMIDE.
Products containing it
- LE QUOTIDIEN DES FEMMES + 50 BiOrganic Nutrition, comprimé, withdrawn from the market
- LEVIFER capsule, withdrawn from the market
- LIBIDON PLUS gélule, withdrawn from the market
- LIBIDON PLUS gélule, withdrawn from the market
- LIBRA gélule, withdrawn from the market
- LIFINOV EFFINOV NUTRITION, gélule, withdrawn from the market
- LIPO(X)PACK Trec Nutrition, capsule, withdrawn from the market
- LIPOXYCUT poudre, flavour fruit rouge, withdrawn from the market
- LIPOXYCUT poudre, flavour pomme verte - citron vert, withdrawn from the market
- LIQUID I.V - HYDRATATION MULTIPIER Citron – Citron vert LIQUID I.V, sachet, flavour citron – citron vert, withdrawn from the market
- LIQUID I.V - HYDRATATION MULTIPIER Fraise LIQUID I.V, sachet, flavour fraise, withdrawn from the market
- LIQUID I.V - HYDRATATION MULTIPIER Fruit de la passion LIQUID I.V, sachet, flavour fruit de la passion, withdrawn from the market
- LIVER STACK Trec Nutrition, capsule, withdrawn from the market
- LR Lifetakt Vita Active Daily Vitamin Drink Red Fruit LR Lifetakt, autre :, flavour fruits rouges, withdrawn from the market
- LYDISS flacon, withdrawn from the market
- Lactoflora Adultes flacon, flavour cerise mandarine, withdrawn from the market
- Lactoflora Adultes flacon, flavour cerise mandarine, withdrawn from the market
- Lactoflora enfants flacon, flavour fraise, withdrawn from the market
- Lactoflora enfants flacon, flavour fraise, withdrawn from the market
- Lecitone Age Laboratoires SYNActifs, gélule, withdrawn from the market
- Lecitone Genius Laboratoires SYNActifs, comprimé, withdrawn from the market
- Lecitone Genius Lecitone, comprimé, withdrawn from the market
- Levure de bière Laboratoires Juvamine, comprimé, withdrawn from the market
- Levure de bière 600mg Laboratoires Juvamine, comprimé, withdrawn from the market
- Levure de bière Sélénium + Zinc Laboratoires Vitarmonyl, comprimé, withdrawn from the market
- Liberdigest Spasmes comprimé, withdrawn from the market
- Liftoff - Orange comprimé, flavour orange, withdrawn from the market
- Liftoff Citron - Citron vert comprimé, flavour citron - citron vert, withdrawn from the market
- Lipo.Actifs gélule, withdrawn from the market
- Lipoxycut poudre, flavour pêche abricot, withdrawn from the market
- Lipoxycut poudre, flavour pomme verte et citron, withdrawn from the market
- Lipoxycut poudre, flavour fruits rouges, withdrawn from the market
- Longévité Complexe Liposomale NovAging, gélule, flavour neutre, withdrawn from the market
- LoriCalm Lorica, autre : poudre orodispersible, flavour fruit rouge menthe, withdrawn from the market
- Lorica Thyroide Lorica, gélule, withdrawn from the market
- Loritirol Lorica, gélule, withdrawn from the market
- Loritirol Lorica, gélule, withdrawn from the market
- Luxéol Vitalité Luxéol, gélule, withdrawn from the market
- M13 Trec Nutrition, poudre, flavour fruit, withdrawn from the market
- M13 Trec Nutrition, poudre, flavour tropicale, withdrawn from the market
- MABON gélule, withdrawn from the market
- MAG 2 CRAMP comprimé, withdrawn from the market
- MAGNEBIANE gélule, withdrawn from the market
- MAGNEBOOSTER bâton / batônnet / stick, flavour arôme naturel de fruits rouges, withdrawn from the market
- MAGNEREL comprimé, withdrawn from the market
- MAGNEREL Laboratoire Santarel, comprimé, withdrawn from the market
- MAGNEREL Laboratoire Santarel, comprimé, withdrawn from the market
- MAGNESIUM NUTRI & CO, gélule, withdrawn from the market
- MAGNESIUM COMPLEXE Laboratoire Physiosens, comprimé, withdrawn from the market
- MAMA ESSENTIALS jolly mama!, gélule, withdrawn from the market
- MARINE COLLAGEN DELUXE capsule, withdrawn from the market
- MEMO.PROTECT Synactifs, gélule, withdrawn from the market
- MEMORIX NATURAMedicatrix, gélule, flavour aucun, withdrawn from the market
- MEN'S CARE HSN, comprimé, withdrawn from the market
- MEN'S MULTIVITAMINS & MINERALS comprimé, withdrawn from the market
- MENOPAUSE 6-en-1 GRANIONS, comprimé, withdrawn from the market
- MENS IMMUNE HEALTH NUTRIMUSCLE, gélule, flavour nature, withdrawn from the market
- MENTAL + AUDISTIM, comprimé, withdrawn from the market
- METADHRYNE ERIC FAVRE, comprimé, withdrawn from the market
- MG-300+9 D-LAB Nutricosmetics, comprimé, withdrawn from the market