Nicotinamide (vitamin B3) in food supplements
8,647 supplements declared in France contain a form of this nutrient
Nicotinamide: in France, a food supplement may not provide more than 54 mg a day (Order of 9 May 2006, not revised since November 2006, Annex III); for adults, EFSA's upper safe limit is 900 mg a day. The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Written Question No 2686, ministry answer published in the Official Journal on 11 February 2025.
What we know about this ingredient
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT04844528 : Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers
RECRUITING · PHASE2 · Chronic Lymphocytic Leukemia, Non-melanoma Skin Cancer (NMSC) · 2025-12-03 · Nicotinamide
- NCT07585006 : Comparative Evaluation of Nicotine Analogs
RECRUITING · PHASE1 · Tobacco-Related Carcinoma, Addiction · 2026-06-26 · nicotinamide
- NCT07808333 : Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial)
NOT_YET_RECRUITING · PHASE2 · Glaucoma, Open-angle, Primary Open Angle Glaucoma (POAG) · 2026-10-13 · Nicotinamide
2026-11-01
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (nicotinamide (vitamine B3)) : sport (1112 produits), immunité (1052 produits), système nerveux (761 produits), cheveux et ongles (735 produits), peau (695 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
Jusqu'où c'est sûr
Pour un adulte, l'EFSAEuropean Food Safety Authority. fixe la limite supérieure de sécurité à 900 mg/j : c'est l'apport quotidien qui, pris sur le long terme, toutes sources alimentaires réunies, ne devrait pas provoquer d'effet indésirable. Au-delà, le risque augmente. Un complément n'est qu'une partie de l'apport.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
La règle en France
En France, la dose journalière recommandée d'un complément ne doit pas apporter plus de 54 mg (arrêté du 9 mai 2006, non révisé depuis novembre 2006). Compl'Alim ne publie pas la dose des produits déclarés : comparez celle de l'étiquette à ce plafond et à la limite de sécurité de l'EFSA.
French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA safety references
Le repère de l'EFSA porte sur l'apport total d'une journée, alimentation et compléments.
| Population | Type | Value |
|---|---|---|
| 1-3 years | Upper limit | 150 mg/j |
| 4-6 years | Upper limit | 220 mg/j |
| 7-10 years | Upper limit | 350 mg/j |
| 11-14 years | Upper limit | 500 mg/j |
| 15-17 years | Upper limit | 700 mg/j |
| adults | Upper limit | 900 mg/j |
| pregnancy | Upper limit | inadequate data |
| breastfeeding | Upper limit | inadequate data |
SCF, 2002a. EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Maximum dose in France
Maximum daily dose per supplement in France: 54 mg, according to the Order of 9 May 2006.
The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
Forms declared in supplements
Union list: vitamin and mineral forms that may be used in a food supplement (Directive 2002/46/EC, Annex II).
Directive 2002/46/EC on food supplements, latest consolidated version (Annex II: forms of vitamins and minerals), retrieved 23 October 2026.
- Nicotinamide 8,534 products on the Union list
- Chlorure de nicotinamide riboside 135 products on the Union list
In cosmetics: NIACINAMIDE.
Products containing it
- No Stress Flash comprimé, withdrawn from the market
- Novophane gélule, withdrawn from the market
- Nu POWER comprimé, withdrawn from the market
- Nuit calme comptoir Botanique, gélule, withdrawn from the market
- Nutralium physionat, gélule, withdrawn from the market
- NutriProtect Ai poudre, withdrawn from the market
- NutriProtect Detox poudre, withdrawn from the market
- Nutricap Croissance Laboratoires Nutrisanté, gélule, withdrawn from the market
- O.Retine Phytocea, gélule, withdrawn from the market
- OH / Alcool autre : sachets + 2 gélules de formules différentes, withdrawn from the market
- OM3 Junior à boire OM3, flacon, withdrawn from the market
- ONE IDEAL poudre, flavour ananas fruits rouges, withdrawn from the market
- OPTEENS NHCO NUTRITION, gélule, flavour néant, withdrawn from the market
- OPTIMA Capillaire Kératine Laboratoires Vitarmonyl, capsule, withdrawn from the market
- OPTIZEN 24 gélule, withdrawn from the market
- ORGANOV 12 gélule, withdrawn from the market
- ORGANOV 12 gélule, withdrawn from the market
- OVOSICARE FERTILITY gélule, withdrawn from the market
- Ocudyne gélule, withdrawn from the market
- One Multi Pure Encapsulations, gélule, withdrawn from the market
- Optimal V gélule, withdrawn from the market
- OstéoRenov Lorica, sachet, withdrawn from the market
- OstéoRénov Lorica, sachet, withdrawn from the market
- OstéoRénov Lorica, poudre, withdrawn from the market
- OstéoRénov Lorica, poudre, flavour fruits exotiques, withdrawn from the market
- OstéoRénov Lorica, poudre, flavour fruits exotiques, withdrawn from the market
- Ours 9 vitamines - format familial Nat&form, gomme, flavour citron, orange, framboise, withdrawn from the market
- Oursons Mutivitaminés Boutique Nature, autre : ourson, withdrawn from the market
- Oxybiane Cell Protect gélule, withdrawn from the market
- Oxybiane Cell Protect gélule, withdrawn from the market
- PA / Pollution autre : sachet + 2 gélules de formules différentes, withdrawn from the market
- PE / Perturbateurs endocriniens autre : 3 composantes : sachets + 2 gélules de formules différentes, withdrawn from the market
- PE / Régulation hormonale autre : 3 composantes : sachets + 2 gélules de formules différentes, withdrawn from the market
- PEAU SAINE Nature Atitude, gélule, withdrawn from the market
- PEAU ÉQUILIBRÉE AKORE SKIN CARE, gélule, withdrawn from the market
- PECEOX gélule, withdrawn from the market
- PECTILIGNE Fringales gélule, withdrawn from the market
- PECTILIGNE VENTRE PLAT gélule, withdrawn from the market
- PERFECT SKIN gélule, withdrawn from the market
- PERMEA REGUL + sachet, withdrawn from the market
- PHANERES + Laboratoires MARTIN-PRIVAT Santé, gélule, withdrawn from the market
- PHOSPHATIDYLSERINE VIT'ALL+, capsule, withdrawn from the market
- PHYCOSENS LABORATOIRE Physiosens, autre : monodose, withdrawn from the market
- PHYTOGLOBAL gélule, withdrawn from the market
- PHYTORUB Sachets sachet, withdrawn from the market
- PHYTOVEX® COMPRIMES NEZ GORGE 3 ACTIONS UPSA, comprimé, withdrawn from the market
- PLATINUM PRE-WORKOUT (Blue raspberry) OPTIMUM NUTRITION, poudre, flavour framboise, withdrawn from the market
- PLATINUM PRE-WORKOUT (Fruit punch) OPTIMUM NUTRITION, poudre, flavour punch aux fruits, withdrawn from the market
- PLATINUM PRE-WORKOUT (Tropical) OPTIMUM NUTRITION, poudre, flavour tropical, withdrawn from the market
- POSITIREL gélule, withdrawn from the market
- POSITIREL Laboratoire Santarel, gélule, withdrawn from the market
- POSITIREL Laboratoire Santarel, gélule, withdrawn from the market
- POSITIREL Laboratoire Santarel, gélule, withdrawn from the market
- POST ESSENTIALS jolly mama!, gélule, withdrawn from the market
- PREBIOMA SENSITIVE poudre, withdrawn from the market
- PREGNANCY FORMULA autre : gélules + capsules, withdrawn from the market
- PREMIUM MULTI (IRON & IODINE FREE) VITAMINALIA, capsule, withdrawn from the market
- PRESERVISION NOCTURNE comprimé, withdrawn from the market
- PRO KERACYS CHEVEUX 4 en 1 GRANIONS, comprimé, flavour /, withdrawn from the market
- PRO KERACYS CHEVEUX GUMMIES 4 EN 1 GRANIONS, gomme, flavour fruits des bois, withdrawn from the market