Nicotinamide (vitamin B3) in food supplements
8,647 supplements declared in France contain a form of this nutrient
Nicotinamide: in France, a food supplement may not provide more than 54 mg a day (Order of 9 May 2006, not revised since November 2006, Annex III); for adults, EFSA's upper safe limit is 900 mg a day. The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Written Question No 2686, ministry answer published in the Official Journal on 11 February 2025.
What we know about this ingredient
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT04844528 : Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers
RECRUITING · PHASE2 · Chronic Lymphocytic Leukemia, Non-melanoma Skin Cancer (NMSC) · 2025-12-03 · Nicotinamide
- NCT07585006 : Comparative Evaluation of Nicotine Analogs
RECRUITING · PHASE1 · Tobacco-Related Carcinoma, Addiction · 2026-06-26 · nicotinamide
- NCT07808333 : Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial)
NOT_YET_RECRUITING · PHASE2 · Glaucoma, Open-angle, Primary Open Angle Glaucoma (POAG) · 2026-10-13 · Nicotinamide
2026-11-01
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (nicotinamide (vitamine B3)) : sport (1112 produits), immunité (1052 produits), système nerveux (761 produits), cheveux et ongles (735 produits), peau (695 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
Jusqu'où c'est sûr
Pour un adulte, l'EFSAEuropean Food Safety Authority. fixe la limite supérieure de sécurité à 900 mg/j : c'est l'apport quotidien qui, pris sur le long terme, toutes sources alimentaires réunies, ne devrait pas provoquer d'effet indésirable. Au-delà, le risque augmente. Un complément n'est qu'une partie de l'apport.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
La règle en France
En France, la dose journalière recommandée d'un complément ne doit pas apporter plus de 54 mg (arrêté du 9 mai 2006, non révisé depuis novembre 2006). Compl'Alim ne publie pas la dose des produits déclarés : comparez celle de l'étiquette à ce plafond et à la limite de sécurité de l'EFSA.
French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA safety references
Le repère de l'EFSA porte sur l'apport total d'une journée, alimentation et compléments.
| Population | Type | Value |
|---|---|---|
| 1-3 years | Upper limit | 150 mg/j |
| 4-6 years | Upper limit | 220 mg/j |
| 7-10 years | Upper limit | 350 mg/j |
| 11-14 years | Upper limit | 500 mg/j |
| 15-17 years | Upper limit | 700 mg/j |
| adults | Upper limit | 900 mg/j |
| pregnancy | Upper limit | inadequate data |
| breastfeeding | Upper limit | inadequate data |
SCF, 2002a. EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Maximum dose in France
Maximum daily dose per supplement in France: 54 mg, according to the Order of 9 May 2006.
The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
Forms declared in supplements
Union list: vitamin and mineral forms that may be used in a food supplement (Directive 2002/46/EC, Annex II).
Directive 2002/46/EC on food supplements, latest consolidated version (Annex II: forms of vitamins and minerals), retrieved 23 October 2026.
- Nicotinamide 8,534 products on the Union list
- Chlorure de nicotinamide riboside 135 products on the Union list
In cosmetics: NIACINAMIDE.
Products containing it
- Manhaé intima équilibre vitavea Laboratoires Nutrisanté, gélule, withdrawn from the market
- MascuPRO Testo & Énergie gélule, flavour neutre, withdrawn from the market
- Maternix G Grossesse capsule, withdrawn from the market
- Maternix G Grossesse capsule, withdrawn from the market
- Maximama comprimé, withdrawn from the market
- Maximama Plus gélule, withdrawn from the market
- Melatonin + L-Tryptophan Gummies Sugar Free Vitaldin, gomme, flavour saveur de mûre, withdrawn from the market
- Melatonin + L-Tryptophan Gummies Sugar Free Vitaldin, gomme, flavour saveur de pêche, withdrawn from the market
- Melatonin + L-Tryptophan Gummies Sugar Free Vitaldin, gomme, flavour saveur de fruits tropicaux, withdrawn from the market
- Melatonin + L-Tryptophan Gummies Sugar Free Vitaldin, gomme, flavour saveur de mûre, withdrawn from the market
- Memoprotect SYNActifs, gélule, withdrawn from the market
- Memoprotect SYNActifs, gélule, withdrawn from the market
- Men's Arginine BiotechUSA, gélule, withdrawn from the market
- Men's Arginine BiotechUSA, gélule, withdrawn from the market
- Menalya Femilyane Women’s Health Ménopause - Gélules Femilyane Women’s Health, gélule, withdrawn from the market
- Meritene Force et Tonus (boîte) Meritene, poudre, flavour vanille, withdrawn from the market
- Meritene Force et Tonus (sachets) Meritene, poudre, flavour vanille, withdrawn from the market
- Mes vitamines de grand flacon, withdrawn from the market
- Michele Diotto Valda, gomme, flavour arôme naturel - goût myrtille, withdrawn from the market
- Minceur Nats'Up, autre : gélules + capsules, withdrawn from the market
- Mineral Vit Magnum Be-Life, gélule, withdrawn from the market
- Mineral classic flacon, withdrawn from the market
- Mood BRAINEFFECT, capsule, withdrawn from the market
- Multi AJR vitamines gélule, withdrawn from the market
- Multi Men comprimé, withdrawn from the market
- Multi Men 18+ 60 tabs PROZIS, comprimé, withdrawn from the market
- Multi Men 35+ 60 tabs PROZIS, comprimé, withdrawn from the market
- Multi PRZ tabs PROZIS, comprimé, withdrawn from the market
- Multi PRZ Professional PROZIS, comprimé, withdrawn from the market
- Multi Women 18+ 60 tabs PROZIS, comprimé, withdrawn from the market
- Multi Women 35+ 60 tabs PROZIS, comprimé, withdrawn from the market
- Multi vitamines Vita Sip fruit des bois Vita sip, bâton / batônnet / stick, flavour fruit des bois, withdrawn from the market
- Multi-Activ gélule, withdrawn from the market
- Multi-Activ gélule, withdrawn from the market
- Multi-Activ gélule, withdrawn from the market
- Multi-Fem ACTIV LEPPIN, comprimé, withdrawn from the market
- Multi-Men ACTIV LEPPIN, comprimé, withdrawn from the market
- Multi-vitamines gélule, withdrawn from the market
- MultiBooster Méthode Chataigner, gélule, withdrawn from the market
- MultiDétox Laboratoires Actinutrition, flacon, withdrawn from the market
- MultiMincir - Nouvelle Formule Méthode Chataigner, gélule, withdrawn from the market
- Multibiane gélule, withdrawn from the market
- Multibiane gélule, withdrawn from the market
- Multibiane Gélule Age Protect gélule, withdrawn from the market
- Multibiane Gélule Age Protect gélule, withdrawn from the market
- Multiitamines gummies Terravita Laboratoire, gomme, flavour orange citron, withdrawn from the market
- Multitonic comprimé, withdrawn from the market
- Multitonic comprimé, withdrawn from the market
- Multitonic comprimé, withdrawn from the market
- Multivit'4G Sénior Forté Pharma, comprimé, withdrawn from the market
- Multivita-kaps gélule, withdrawn from the market
- Multivitamines manutra, bâton / batônnet / stick, withdrawn from the market
- Multivitamines Bioconseils, gomme, withdrawn from the market
- Multivitamines manutra, sachet, withdrawn from the market
- Multivitamines & Minéraux à croquer Laboratoires Juvamine, comprimé, withdrawn from the market
- Multivitamines 45 + gélule, withdrawn from the market
- Multivitamines BOOST Laboratoires Vitarmonyl, comprimé, withdrawn from the market
- Multivitamines Energy Fit & Healthy, comprimé, withdrawn from the market
- Multivitamines Global vitavea Laboratoires Nutrisanté, gélule, withdrawn from the market
- Multivitamines Multiminéraux Boutique Nature, gélule, withdrawn from the market