Nicotinamide (vitamin B3) in food supplements
8,647 supplements declared in France contain a form of this nutrient
Nicotinamide: in France, a food supplement may not provide more than 54 mg a day (Order of 9 May 2006, not revised since November 2006, Annex III); for adults, EFSA's upper safe limit is 900 mg a day. The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Written Question No 2686, ministry answer published in the Official Journal on 11 February 2025.
What we know about this ingredient
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT04844528 : Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers
RECRUITING · PHASE2 · Chronic Lymphocytic Leukemia, Non-melanoma Skin Cancer (NMSC) · 2025-12-03 · Nicotinamide
- NCT07585006 : Comparative Evaluation of Nicotine Analogs
RECRUITING · PHASE1 · Tobacco-Related Carcinoma, Addiction · 2026-06-26 · nicotinamide
- NCT07808333 : Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial)
NOT_YET_RECRUITING · PHASE2 · Glaucoma, Open-angle, Primary Open Angle Glaucoma (POAG) · 2026-10-13 · Nicotinamide
2026-11-01
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (nicotinamide (vitamine B3)) : sport (1112 produits), immunité (1052 produits), système nerveux (761 produits), cheveux et ongles (735 produits), peau (695 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
Jusqu'où c'est sûr
Pour un adulte, l'EFSAEuropean Food Safety Authority. fixe la limite supérieure de sécurité à 900 mg/j : c'est l'apport quotidien qui, pris sur le long terme, toutes sources alimentaires réunies, ne devrait pas provoquer d'effet indésirable. Au-delà, le risque augmente. Un complément n'est qu'une partie de l'apport.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
La règle en France
En France, la dose journalière recommandée d'un complément ne doit pas apporter plus de 54 mg (arrêté du 9 mai 2006, non révisé depuis novembre 2006). Compl'Alim ne publie pas la dose des produits déclarés : comparez celle de l'étiquette à ce plafond et à la limite de sécurité de l'EFSA.
French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA safety references
Le repère de l'EFSA porte sur l'apport total d'une journée, alimentation et compléments.
| Population | Type | Value |
|---|---|---|
| 1-3 years | Upper limit | 150 mg/j |
| 4-6 years | Upper limit | 220 mg/j |
| 7-10 years | Upper limit | 350 mg/j |
| 11-14 years | Upper limit | 500 mg/j |
| 15-17 years | Upper limit | 700 mg/j |
| adults | Upper limit | 900 mg/j |
| pregnancy | Upper limit | inadequate data |
| breastfeeding | Upper limit | inadequate data |
SCF, 2002a. EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Maximum dose in France
Maximum daily dose per supplement in France: 54 mg, according to the Order of 9 May 2006.
The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
Forms declared in supplements
Union list: vitamin and mineral forms that may be used in a food supplement (Directive 2002/46/EC, Annex II).
Directive 2002/46/EC on food supplements, latest consolidated version (Annex II: forms of vitamins and minerals), retrieved 23 October 2026.
- Nicotinamide 8,534 products on the Union list
- Chlorure de nicotinamide riboside 135 products on the Union list
In cosmetics: NIACINAMIDE.
Products containing it
- PROBIOBOOST Flore intime Pilote Fleurance Nature, gélule, flavour aucun, withdrawn from the market
- PURE PRE-WORKOUT EAFIT, poudre, flavour fruits rouges, withdrawn from the market
- PURE PRE-WORKOUT EAFIT, poudre, flavour fruits rouges, withdrawn from the market
- Peau hâlée Nadora, gélule, withdrawn from the market
- Peceox Nurilia, autre : gelule + comprimé, withdrawn from the market
- Phase 2 poudre, withdrawn from the market
- Physiobase gélule, withdrawn from the market
- Physiocap Laboratoires Yves Ponroy, gélule, withdrawn from the market
- PhytoRub Confort sachet, withdrawn from the market
- Plaisirs intimes gélule, withdrawn from the market
- Pollution atmosphérique autre : sachet + 2 gélules de formules différentes, withdrawn from the market
- Postmenox comprimé, withdrawn from the market
- Pregnavital gélule, withdrawn from the market
- Premenox autre : comprimés+gélules, withdrawn from the market
- Probiol Sekoya, poudre, withdrawn from the market
- Procrelia - Femme Nurilia, comprimé, withdrawn from the market
- ProgéniT + Spécial Femme comprimé, withdrawn from the market
- ProgéniT+ H comprimé, withdrawn from the market
- PropioForce Lorica, gélule, withdrawn from the market
- PropioForce Lorica, sachet, withdrawn from the market
- PropioForce Lorica, sachet, withdrawn from the market
- PropioForce Lorica, gélule, withdrawn from the market
- PropioForce Lorica, poudre, flavour naturel, withdrawn from the market
- Préparation Yves Ponroy, sachet, withdrawn from the market
- Préparation N°23 autre : gélule et compte-gouttes, withdrawn from the market
- Préparation N°25 autre : gélule, stick et compte-gouttes, withdrawn from the market
- QUANTACOEUR PHYTOQUANT, gélule, withdrawn from the market
- QUARKS CORGENIC, comprimé, withdrawn from the market
- QUOTIDOSE Laboratoires MARTIN-PRIVAT Santé, autre : gélule / capsule, withdrawn from the market
- Quantavital Sport Phytoquant, gélule, withdrawn from the market
- Quarks comprimé, withdrawn from the market
- Quarks comprimé, withdrawn from the market
- R CAPS CHUTE CLINERIENCE, comprimé, withdrawn from the market
- RBC FORCE MAX 3C Pharma, sirop, withdrawn from the market
- RED YEAST RICE NUTRALIE, capsule, withdrawn from the market
- RED YEAST RICE NUTRALIE, capsule, withdrawn from the market
- RED YEAST RICE NUTRALIE, gélule, withdrawn from the market
- RED YEAST RICE NUTRALIE, capsule, withdrawn from the market
- RENFORT + AUDISTIM, comprimé, withdrawn from the market
- REPONSE CARDIOVASCULAIRE gélule, withdrawn from the market
- RIPPED Pre-Workout Prozis, poudre, flavour cola, withdrawn from the market
- RIPPED Pre-Workout Prozis, poudre, flavour citron, withdrawn from the market
- RIPPED Pre-Workout Prozis, poudre, flavour limonade rose, withdrawn from the market
- Raw Boost Addict Sport Nutrition, poudre, withdrawn from the market
- Regenum Lorica, poudre, flavour agrumes, withdrawn from the market
- Regenum Lorica, comprimé, withdrawn from the market
- Regenum Forte Lorica, sachet, withdrawn from the market
- Regenum Forte Lorica, sachet, withdrawn from the market
- Regenum Forte Lorica, sachet, flavour agrumes, withdrawn from the market
- Regenum Forte Lorica, bâton / batônnet / stick, flavour agrumes, withdrawn from the market
- Regenum Forte Lorica, bâton / batônnet / stick, flavour agrumes, withdrawn from the market
- Relax + Dieti Natura, gélule, withdrawn from the market
- Richelet Protection Cellulaire Selenium + L-cysteine - Force du cheveu capsule, withdrawn from the market
- Rubaxan Articulations Rubaxan, sachet, withdrawn from the market
- Régénum Lorica, gélule, withdrawn from the market
- Régénum Lorica, gélule, withdrawn from the market
- Régénum gélule Lorica, gélule, withdrawn from the market
- Régénum gélules Lorica, gélule, withdrawn from the market
- Régénum pot Lorica, poudre, flavour pêche, withdrawn from the market
- Régénum pot Lorica, poudre, flavour pêche, withdrawn from the market