Lysine in food supplements
771 supplements declared in France contain Lysine as a substance or active ingredient.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
BIOLOGICAL ACTIVITIES: Antialkalotic; antiherpetic; essential; hypoarginanemic
Biochemical and nutritional research, pharmaceuticals, culture media, fortification of foods and feed (wheat flour), nutrient and dietary supplement, animal feed additive
Enrichment of cereals and feeds.
Medical use: treatment of hypochloremia, alkalosis /lysine hydrochloride/
Reported uses
Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#3864]
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · USDA; Dr. Duke's Phytochemical and Ethnobotanical Databases. Plants with a chosen chemical. Lysine. Washington, DC: US Dept Agric, Agric Res Service. Available from, as of August 17, 2010: https://www.ars-grin.gov/duke/; Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 86 (1985); Burdock, G.A. (ed.). Fenaroli's Handbook of Flavor Ingredients. 6th ed.Boca Raton, FL 2010, p. 1110.
Use classification
Cosmetics -> Skin conditioning; Hair conditioning; Antistatic
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 119 taxa; examples: Morchella angusticeps, Morchella crassipes, Citrus grandis, Citrus medica, Pinus densiflora.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
A process combining chemical and microbiological techniques for the production of L-lysine was introduced by Toray Industries; /in this process/, alpha-amino-e-caprolactam (ACL) is formed from cyclohexanol... this intermediate is then hydrolyzed with L-ACL-hydrolase to yield L-lysine
Extraction of natural proteins, synthetically by fermentation of glucose or other carbohydrates and by synthesis from caprolactum
Isolation from acid-hydrolyzed proteins (casein, fibrin or blood corpuscle paste)
The usual raw material for the fermentation production of L-lysine is molasses...high performance microbes belong to the species Corynebacterium glutamicum or Brevibactrium lactofermentum
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 71 (1985); Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 887.
Appearance
Colorless crystals
Needles from water, hexagonal plates from dilute alcohol
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977.
Taste described
Sweet/bitter
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT05210504 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 3
COMPLETED · PHASE1 · Diabetes Mellitus, Type 2 · 2024-06-05 · L-Lysine
- NCT06580145 : Leucine in Midlife Depression
RECRUITING · PHASE2 · Major Depression · 2026-09-11 · L-lysine; L-lysine (synonym declared in the registry)
- NCT04417218 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 2
COMPLETED · NA · Healthy · 2023-12-21 · Lysine
2026-11-01
Other names: L-lysine (French), L-lysine (English).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: LYSINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Lysine) : sport (252 produits), cheveux et ongles (110 produits), peau (54 produits), articulations (42 produits), immunité (42 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 8 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 953 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 1330 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 133 | 480 | 0.009 | 7,400 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- Complexe de Pousse D-LAB Nutricosmetics, gélule, declared in 2019
- Complexe fer intégral Terravita, gélule, declared in 2026
- Complexe équilibre enzymes premium gélule, declared in 2021
- Coriase Hair & Vital poudre, declared in 2025
- Coup de Foudre Feel Pure, gélule, declared in 2025
- Creatmax Grape Juice (Raisin) NTI, poudre, flavour grape juice (raisin), declared in 2016
- Creatmax Ice Blue Berry NTI, poudre, flavour ice blue berry (framboise), declared in 2016
- Creatmax Orange NTI, poudre, flavour orange, declared in 2016
- Cure de peau nuit BioProphyl GmbH, gélule, declared in 2025
- D Gen Laboratoires Activa, comprimé, declared in 2021
- DEPUR SLIM DRASANVI, ampoule, flavour menthe, declared in 2016
- DETOX capsule, declared in 2023
- DHA Green Nutrixeal, gélule, declared in 2020
- DHA végétal DYNVEO, gélule, declared in 2021
- Daniel Angerer Medical Beauty, gélule, flavour neutre, declared in 2024
- Digest + gélule, declared in 2021
- Dr Rath Arteriforte Dr. Rath, gélule, declared in 2023
- Dr. Rath EpiQuercican YouCellTM-CA Dr. Rath, gélule, declared in 2023
- Dr. Rath LyCin Dr. Rath, poudre, declared in 2023
- Dr. Rath LyCin Tab Dr. Rath, comprimé, declared in 2023
- Dr. Rath ProlysinC Dr. Rath, gélule, declared in 2023
- Dr. Rath Vitacor plus Formule de base, gélule, declared in 2023
- EAA Institut Triple A, poudre, declared in 2026
- EAA poudre, declared in 2024
- EAA HIVITAL FOODS, comprimé, declared in 2024
- EAA poudre, declared in 2023
- EAA EDEN NUTRITION, poudre, flavour pomme, declared in 2023
- EAA EDEN NUTRITION, poudre, flavour pasteque, declared in 2023
- EAA Trained by JP, poudre, flavour strawberry & kiwi, declared in 2026
- EAA poudre, flavour pfirsich, declared in 2025
- EAA poudre, declared in 2025
- EAA - Acides Aminés Essentiels Prozis, poudre, flavour pamplemousse, declared in 2020
- EAA - Acides Aminés Essentiels Prozis, poudre, flavour limonade rose, declared in 2020
- EAA - Acides Aminés Essentiels Prozis, poudre, flavour ananas et menthe, declared in 2020
- EAA - Acides Aminés Essentiels Prozis, poudre, flavour ananas, declared in 2020
- EAA - Acides Aminés Essentiels Prozis, poudre, flavour gingembre et citron, declared in 2020
- EAA - Acides Aminés Essentiels Prozis, poudre, flavour kiwi, declared in 2020
- EAA - Acides Aminés Essentiels Prozis, poudre, flavour melon, declared in 2020
- EAA - Acides Aminés Essentiels Prozis, poudre, flavour mojito, declared in 2020
- EAA - Acides Aminés Essentiels Prozis, poudre, flavour pitaya, declared in 2020
- EAA - Acides Aminés Essentiels PROZIS, poudre, flavour poire, declared in 2019
- EAA 300 G Spang NUTRITION, poudre, flavour citron, declared in 2025
- EAA 300 G NUTRIPRIME, poudre, declared in 2025
- EAA 300 g BRAVIS NUTRITION, poudre, flavour citron, declared in 2025
- EAA 6000mg HIVITAL FOODS, comprimé, declared in 2024
- EAA 9 ESSENTIAL AMINO ACIDS (BLUEBERRY DRAGONFRUIT TASTE) poudre, flavour blueberry dragonfruit taste, declared in 2026
- EAA 9 ESSENTIAL AMINO ACIDS (CACTUS LIME TASTE) poudre, flavour cactus lime taste, declared in 2026
- EAA 9 ESSENTIAL AMINO ACIDS (CANDY LEMON TASTE) poudre, flavour candy lemon taste, declared in 2026
- EAA 9 ESSENTIAL AMINO ACIDS (CHERRY TASTE) poudre, flavour cherry taste, declared in 2026
- EAA 9 ESSENTIAL AMINO ACIDS (COLA LEMON TASTE) poudre, flavour cola lemon taste, declared in 2026
- EAA 9 ESSENTIAL AMINO ACIDS (GALAXY PUNCH TASTE) poudre, flavour galaxy punch taste, declared in 2026
- EAA 9 ESSENTIAL AMINO ACIDS (GREEN APPLE TASTE) poudre, flavour green apple taste, declared in 2026
- EAA 9 ESSENTIAL AMINO ACIDS (ICE TEA LEMON TASTE) poudre, flavour ice tea lemon taste, declared in 2026
- EAA 9 ESSENTIAL AMINO ACIDS (ICE TEA PEACH TASTE) poudre, flavour ice tea peach taste, declared in 2026
- EAA 9 ESSENTIAL AMINO ACIDS (MANGO PINEAPPLE TASTE) poudre, flavour mango pineapple taste, declared in 2026
- EAA 9 ESSENTIAL AMINO ACIDS (STRAWBERRY WATERMELON TASTE) poudre, flavour strawberry watermelon taste, declared in 2026
- EAA 9 ESSENTIAL AMINO ACIDS (SWEET ORANGE TASTE) poudre, flavour sweet orange taste, declared in 2026
- EAA 9 ESSENTIAL AMINO ACIDS (SWEET PEAR TASTE) poudre, flavour sweet pear taste, declared in 2026
- EAA 9 ESSENTIAL AMINO ACIDS (WILDBERRY TASTE) poudre, flavour wildberry taste, declared in 2026
- EAA 9 ESSENTIAL AMINO ACIDS (cherry) GEN®GERMAN ELITE NUTRITION, poudre, flavour cerise, declared in 2025
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